Mucoadhesion and mucosa-mimetic materials—A mini-review
نویسندگان
چکیده
منابع مشابه
Mucoadhesion and mucosa-mimetic materials--A mini-review.
Mucoadhesion describes an attractive interaction between dosage form and mucosal membrane. The evaluation of mucoadhesive excipients often requires the use of ex vivo mucosal tissues taken from laboratory animals. These can be difficult to source, highly heterogeneous, and require the use of animal products. Thus, from both a user-convenience and ethical point-of-view, it is desirable to produc...
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The detachment forces of various polymers are frequently measured to determine their mucoadhesion strength. As the process of mucoadhesion is a consequence of interactions between the mucus layer on mucosa and mucoadhesive polymers, it is greatly dependent on mucus and polymer structure including their charge. It is also known that the glycosaminoglycan layer, which covers the urinary bladder m...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2015
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2015.09.064